Market Pulse53Neutral

CRISPR Therapeutics AGOpportunity Rank #325(CRSP) Intrinsic Value & DCF Analysis (2026)

Sector: Healthcare

Current Price

$47.53

Last updated: Jul 24, 2026

Price vs Intrinsic Value

$47.53
Price
$17.00
Intrinsic Value
Overvalued by 64%MOS: $13.60

Fundamental Score

3/100
Bearish

Weighted across 6 signals

Narrative Score

56/100
Improving

No change vs previous

Trend Score

13/100
Weak

As of 2026-07-24

Still researching stocks one at a time?

Intrinziq helps you:

  • Turn your stock-picking rules into repeatable strategies
  • Find better setups across hundreds of stocks automatically
  • Backtest your strategy before putting money to work
See How It Works

The intrinsic value of CRISPR Therapeutics AG (CRSP) is estimated at $17.00 per share based on a 10-year discounted cash flow (DCF) analysis. At the current price of $47.53, the stock appears overvalued relative to its projected cash flow fundamentals. This estimate assumes a -60.50% long-term growth rate and a 10.00% discount rate (calculated: 9.95%), reflecting expected future free cash flow and cost of capital.

The intrinsic value of CRISPR Therapeutics AG (CRSP) is estimated at $17.00 per share based on a 10-year discounted cash flow (DCF) analysis. At the current price of $47.53, the stock appears overvalued relative to its projected cash flow fundamentals. This estimate assumes a -60.50% long-term growth rate and a 10.00% discount rate (calculated: 9.95%), reflecting expected future free cash flow and cost of capital.

Valuation Details

$17.00
-64.23% downside
20% margin of safety: $13.60
Years: 10Growth Rate: -60.50%
Want to create your own valuation? Create a free account.

Capital Efficiency

Average Quarterly ROIC
-1275.72%
Cost of Capital (estimated)7%
Value StatusUnderperforming Capital

The company is earning below its required return. This may indicate inefficient use of capital or excess cash that isn't being reinvested.

Complete historical ROIC is available with
.

Fundamental Details

3/100
BearishWeighted across 6 signals
DCF Discount
64.2% premium to price
0
FCF Yield
-8.7% trailing FCF yield
0
ROIC vs WACC
ROIC -1275.7% vs WACC 7.0% (-182.2x)
0
Net Debt / FCF
4.7x net debt to FCF
0
Buybacks
Share count growing
30
FCF CAGR (5Y)
-64.6% 5Y FCF CAGR (adjusted)
0
Pressure from: DCF Discount, FCF Yield.

Narrative Details

56/100
Improving
Vs 6-Month Baseline:Average (43rd pct)Weighted across 3 recent drivers
Trend: StableConfidence: 87%Updated: 1d ago
Sources: 47 (43 News · 4 Analyst)
Drivers(last 30 days)
3 regulatory scrutiny+0.3
40 news sentiment+0.3
4 analyst reiterations0.0

Trend Details

13/100
WeakAs of 2026-07-24310 daily bars used
6M Relative Strength vs SPY-30.7%
3M Relative Strength vs SPY-20.0%
Price vs 21 EMA-8.8%
Price vs 21 EMA9 · -8.8%
Price vs 50 EMA9 · -10.8%
21 EMA vs 50 EMA32 · -2.3%
3M RS vs SPY3 · -20.0%
6M RS vs SPY3 · -30.7%
Distance from 52W High21 · -39.4%

Investment Coach

Updating... 44d ago
AVOIDConfidence: 89%
Thesis
CRISPR Therapeutics AG is significantly overvalued with its current price 65.7% above the estimated fair value, supported by weak fundamentals and negative free cash flow yield. The company's returns are trailing its cost of capital, indicating poor capital efficiency and financial health.
Key Risk
Continued deterioration in financial performance or failure to improve return on invested capital relative to the weighted average cost of capital could further depress valuation.
Signals To Watch
  • Price moves to at least a mid-teens discount to fair value
  • Sustained improvement in ROIC versus WACC spread
  • Meaningful shifts in narrative trend and fundamental score
Ask the Coach - Available with
Historical Growth Rates
Free Cash Flow- - -Trend CAGR (Adjusted): -60.50%5 Year CAGR (Adjusted): -74.98%

Free Cash Flow (in millions)

TTM202520242023202220212020201920182017201620152014
-$399-$344-$141-$251-$459$621-$220$63-$93-$62-$52$61-$5

How Intrinziq Estimates Fair Value

Intrinziq estimates CRISPR Therapeutics AG's intrinsic value using a discounted cash flow (DCF) model based on free cash flow trends and a market-based discount rate. The model projects future cash flows over ten years and discounts them using a market return assumption to estimate fair value.

CRISPR Therapeutics AGHealthcare

CRISPR Therapeutics AG (CRSP) is a biotechnology firm dedicated to pioneering gene-based medicines for severe diseases. The company achieves this through its exclusive Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) technology, which enables precise and targeted alterations to an organism's genetic code. Its extensive pipeline includes therapeutic candidates spanning multiple medical areas, such as blood disorders (hemoglobinopathies), various cancers (oncology), regenerative medicine, and rare conditions. The company's flagship investigational therapy is CTX001, an ex vivo CRISPR gene-edited treatment. This therapy aims to benefit patients with transfusion-dependent beta-thalassemia or severe sickle cell disease by modifying their own hematopoietic stem cells to markedly boost the production of fetal hemoglobin within red blood cells. CRISPR Therapeutics is also advancing several other genetically engineered allogeneic (donor-sourced) CAR-T investigational therapies: CTX110, designed to combat cluster of differentiation 19-positive malignancies; CTX120, which targets B-cell maturation antigen for multiple myeloma that has relapsed or proven resistant to previous treatments; and CTX130, focused on Cluster of Differentiation 70 for a spectrum of solid tumors and blood cancers. Furthermore, the company is developing VCTX210, an immune-evasive, gene-edited stem cell-derived product candidate for treating type 1 diabetes. It is also pursuing various in vivo gene-editing initiatives aimed at addressing disorders affecting the liver, lungs, muscles, and central nervous system. The company has forged strategic alliances with significant partners, including Bayer Healthcare LLC, Vertex Pharmaceuticals Incorporated, ViaCyte, Inc., Nkarta, Inc., and Capsida Biotherapeutics. CRISPR Therapeutics AG was established in 2013 and maintains its headquarters in Zug, Switzerland.